Journal article
Combined physical and cognitive training for older adults with and without cognitive impairment: A systematic review and network meta-analysis of randomized controlled trials
HM Gavelin, C Dong, R Minkov, A Bahar-Fuchs, KA Ellis, NT Lautenschlager, ML Mellow, AT Wade, AE Smith, C Finke, S Krohn, A Lampit
Ageing Research Reviews | ELSEVIER IRELAND LTD | Published : 2021
Abstract
Combining physical exercise with cognitive training is a popular intervention in dementia prevention trials and guidelines. However, it remains unclear what combination strategies are most beneficial for cognitive and physical outcomes. We aimed to compare the efficacy of the three main types of combination strategies (simultaneous, sequential or exergaming) to either intervention alone or control in older adults. Randomized controlled trials of combined cognitive and physical training were included in multivariate and network meta-analyses. In cognitively healthy older adults and mild cognitive impairment, the effect of any combined intervention relative to control was small and statistical..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
We thank Sahar Aghajari for help with data entry and the authors of primary studies for providing data and advice. MLM was funded by a scholarship from Dementia Australia. ATW is funded by a grant from the Australian National Health and Medical Research Council (NHMRC GNT1171313). AL is funded by a CR Roper Fellowship from the University of Melbourne.